Seminars & Events
Friday, October 4, 2013: Dr. Laurie Ryan, SMCM '86 (National Institute on Aging) will speak on "Alzheimer's Disease: Targets and Treatments" at 3:00 pm in Goodpaster Hall 195.
Monday, October 21, 2013: Dr. Greg Elmer (University of Maryland Baltimore) will speak on "Domains and Constructs in Motivation: Where Does the Habenula Fit In?" at 4:45 pm in Goodpaster Hall 195.
Friday, October 25, 2013: Dr. Terry Davidson (American University) will speak on "Why We Overeat and Become Obese? It Could be What We Think!" at 3:00 pm in Goodpaster Hall 195.
Dr. Gwen Calhoon '06 recently received her Ph.D. in Neuroscience from the University of Maryland Baltimore, and was inducted into Nu Rho Psi.
Cole, Trey (2010). The Effects of Adolescent Stress on Adult Working Memory and Susceptibility to Drug Addiction in a Neurodevelopmental Animal Model of Schizophrenia. Mentor: Dr. Anne Marie Brady
Schizophrenic patients experience significant amounts of stress during their daily lives. Also, schizophrenics suffer from impaired working memory and increased rates of drug addiction. Chronic stress produces similar effects. A current neurodevelopmental animal model of schizophrenia involves neonatal ventral hippocampus excitotoxic lesions (NVHL), which produce an array of schizophrenic-like symptoms in adulthood. The current study investigated the effects of the NVHL and 6-hr daily restraint stress for 3 wks during adolescence on working memory in the novel object recognition test and drug-seeking behaviors in the conditioned place preference test. Results showed that restraint stress impaired working memory performance, but the NVHL did not. Neither variables affected conditioned-place preference performance. NVHL + restraint combined to increase locomotor activity in the conditioned place preference task. Possible explanations for the non-effects of NVHL are discussed. Implications include the need to reduce adolescent stress, especially when there is evidence of early insult to the hippocampus.