Seminars & Events
Thursday, September 11, 2014: Dr. Bevil Conway (Wellesley College) will speak on his research in visual neuroscience and color at 4:30 pm in Goodpaster Hall 195.
Monday, October 27, 2014: Dr. Todd Gould (University of Maryland Baltimore) will speak on "Genes to behaviors to treatments in bipolar disorder" at 4:45 pm in Goodpaster Hall 195.Friday, December 5, 2014: Dr. Brian Mathur (University of Maryland Baltimore) will speak on "Braking bad: Aberrant inhibitory neurotransmission in addiction" at 3:00 pm in Goodpaster Hall 195.
Smith, Elizabeth S. (2010). Combining Two Models of Schizophrenia: Behavioral and Neuronal Implications. Mentor: Dr. Anne Marie Brady
The neonatal ventral hippocampal lesion (NVHL) as well as isolation rearing are rodent models of schizophrenia that produce similar behavioral deficits in sensorimotor gating, social behavior, and spatial working memory in conjunction with similar neuropathologies. The combination of both of these models in rats produces an additive effect on locomotor activity and on structural deficits within the prefrontal cortex (PFC) and nucleus accumbens (NAcc). In this study, the combination of isolation rearing and the NVHL model was examined in sensorimotor gating, social behavior, spatial working memory and neuronal activity within the PFC and NAcc. There was no additive effect of combining isolation rearing and the NVHL on these tasks or on neuronal activity within the PFC and NAcc.