Seminars & Events
Friday, October 4, 2013: Dr. Laurie Ryan, SMCM '86 (National Institute on Aging) will speak on "Alzheimer's Disease: Targets and Treatments" at 3:00 pm in Goodpaster Hall 195.
Monday, October 21, 2013: Dr. Greg Elmer (University of Maryland Baltimore) will speak on "Domains and Constructs in Motivation: Where Does the Habenula Fit In?" at 4:45 pm in Goodpaster Hall 195.
Friday, October 25, 2013: Dr. Terry Davidson (American University) will speak on "Why We Overeat and Become Obese? It Could be What We Think!" at 3:00 pm in Goodpaster Hall 195.
Dr. Gwen Calhoon '06 recently received her Ph.D. in Neuroscience from the University of Maryland Baltimore, and was inducted into Nu Rho Psi.
Chiappelli, J. (2004, May). Behavioral Functions of 5-HT1A Receptors in Rat Orbitofrontal Cortex.
Mentor: Dr. Aileen Bailey
Cannula were implanted in the orbitofrontal cortex (OFC), a prefrontal region of the brain, of 17 rats. The behavior of these animals was observed after intracerebral infusion or intraperitoneal injection of 8-OH-DPAT, a serotonin- 1A agonist. Behavior paradigms used were the open field, social interaction, forced swim and prepulse inhibition tests. Intracerebral infusion of 8-OH-DPAT increased exploratory behavior, had a weak anxiety-reducing effect, and decreased social interaction of the rats, but did not affect depression like behavior or sensorimotor gating. Systemic injection of 8-OH-DPAT had an antidepressant-like effect. Results indicate a role of 5-HT1A receptors in the OFC in regulating social and emotional behaviors, and may have implications for psychopathology.
Read the paper (pdf format, 1.71 MB)