Seminars & Events
Friday, October 4, 2013: Dr. Laurie Ryan, SMCM '86 (National Institute on Aging) will speak on "Alzheimer's Disease: Targets and Treatments" at 3:00 pm in Goodpaster Hall 195.
Monday, October 21, 2013: Dr. Greg Elmer (University of Maryland Baltimore) will speak on "Domains and Constructs in Motivation: Where Does the Habenula Fit In?" at 4:45 pm in Goodpaster Hall 195.
Friday, October 25, 2013: Dr. Terry Davidson (American University) will speak on "Why We Overeat and Become Obese? It Could be What We Think!" at 3:00 pm in Goodpaster Hall 195.
Dr. Gwen Calhoon '06 recently received her Ph.D. in Neuroscience from the University of Maryland Baltimore, and was inducted into Nu Rho Psi.
Dippel, W. Chris (2012). Cognitive and behavioral impairments evaluated in the neonatal ventral hippocampus lesion rat model of schizophrenia. (Mentor: A.M. Brady)
The neonatal ventral hippocampus lesion (NVHL) is a proposed rat model for schizophrenia. The present study assessed the effects of the NVHL in social interaction, pre-pulse inhibition, spontaneous locomotion, response to amphetamine, set-shifting, and reversal learning. Rats with an NVHL showed deficits in pre-pulse inhibition, and set-shifting as well as a stronger response to amphetamine. Few effects were found in social interaction, and there was no effect during reversal learning. Pre-exposed rats made more perseverative errors during the set-shift task suggesting the NVHL causes impairments in PFC functioning. Percent pre-pulse inhibition was negatively correlated with trials to criterion on the shift day of the set-shifting task, response to amphetamine, and spontaneous locomotion suggesting there may be a relationship between behavior deficits elicited by the NVHL.