Seminars & Events
Thursday, September 11, 2014: Dr. Bevil Conway (Wellesley College) will speak on his research in visual neuroscience and color at 4:30 pm in Goodpaster Hall 195.
Monday, October 27, 2014: Dr. Todd Gould (University of Maryland Baltimore) will speak on "Genes to behaviors to treatments in bipolar disorder" at 4:45 pm in Goodpaster Hall 195.Friday, December 5, 2014: Dr. Brian Mathur (University of Maryland Baltimore) will speak on "Braking bad: Aberrant inhibitory neurotransmission in addiction" at 3:00 pm in Goodpaster Hall 195.
Ward, Caitlin (2007). Conditioned Place Preference and the Effect of Dopamine Antagonism on Cocaine Reward in Adolescent and Adult Rats.
Mentor: Dr. Anne Marie Brady
Drug addiction is regulated by dopamine pathways in the human brain. Based on developmental differences between the adult and adolescent brain, it was hypothesized that adolescent and adult rats would respond differentially to treatment with drugs intended for cocaine anti-abuse. It was hypothesized that flupenthixol would block place preference in rats, and would be less effective in adolescent rats. Results show that rats demonstrated place preference, but found no differences between adolescents and adults, or groups receiving saline or flupenthixol prior to testing. Flupenthixol suppressed activity and movement, and had a greater affect on the suppression of movement in adult rats. These results suggest that behavioral responses to dopamine antagonism are different in adult and adolescent subjects.