Seminars & Events
Friday, October 4, 2013: Dr. Laurie Ryan, SMCM '86 (National Institute on Aging) will speak on "Alzheimer's Disease: Targets and Treatments" at 3:00 pm in Goodpaster Hall 195.
Monday, October 21, 2013: Dr. Greg Elmer (University of Maryland Baltimore) will speak on "Domains and Constructs in Motivation: Where Does the Habenula Fit In?" at 4:45 pm in Goodpaster Hall 195.
Friday, October 25, 2013: Dr. Terry Davidson (American University) will speak on "Why We Overeat and Become Obese? It Could be What We Think!" at 3:00 pm in Goodpaster Hall 195.
Dr. Gwen Calhoon '06 recently received her Ph.D. in Neuroscience from the University of Maryland Baltimore, and was inducted into Nu Rho Psi.
Konka, K.G., and Bailey, A.M. (2010, November). Investigation of the effects of pup postnatal exposure to fluoxetine on adult rat emotional and motor behavior.
Poster presented at the Society for Neuroscience Annual Meeting, San Diego, CA.
Women diagnosed with post-partum depression are often treated with selective serotonin reuptake inhibitors (SSRI). SSRIs can readily pass through the mother’s breast milk to the infant during breast feeding. We aimed here to examine the long-term neurobehavioral and developmental effects of SSRI exposure to infants during lactation. In the present study, dams were given 12 mg/kg of fluoxetine per day in crushed food pellets. Male rat pups were exposed to fluoxetine through dam’s milk from post-natal day (PD) 8 to PD 21. Rats were allowed to mature undisturbed until adulthood ( > PD65) when they underwent behavioral and emotional testing. Fluoxetine exposed rats spent significantly less time in the closed arms of an elevated plus maze than control rats. Fluoxetine-exposed rats did not show differences in a novel open field or in a forced swim test when compared to control animals. However, rats exposed to fluoxetine had a significantly lower latency to fall and reached a lower rotation per minute (RPM) than control animals when tested on the rotarod. These results indicate that postnatal exposure to fluoxetine may have long-term emotional and motor side effects that should be considered.